Non-rhabdomyosarcoma soft tissue sarcomas (NRSTS) make up about 8% of all childhood cancers. The cause(s) of these tumors is not known. Despite treatments, including surgery and chemotherapy, the tumors frequently return and spread to other sites in the body. Carmen Torres-Zárate and collaborators at the Instituto Nacional de Pediatíra and Universidad Autónoma de México, in Mexico City, Mexico, studied the possible reason for the recurrence of NRSTS, with a focus on the enzymes that perform drug metabolism in many tissues in the body.
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